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Products » ALEXYS Analyzers » Aminoglycoside Analyzer

Aminoglycoside Analyzer

ALEXYS analyzer for aminoglycoside antibiotics

  • According US and European Pharmacopeia
  • One Analyzer for all aminoglycosides
  • FlexCell with easy exchangeable electrode
  • Reproducible and robust analysis

The Aminoglycoside Analyzer can be used for the analysis of all type of aminoglycosides such as: Amikacin, Framycetin, Gentamicin, Kanamycin, Lincomycin, Netilmicin, Neomycin, Spectinomycin, Streptomycin, Tobramycin, etc.

The system is dedicated to the analysis of these antibiotics in pharmaceutical formulations and bulk products. Aminoglycosides are manufactured by a fermentation process and the main constituents as well as impurities and by-products must be identified and quantified for USP and EP compliance requirements. How to interpret the system suitability requirements and the flexibility in allowable adjustments is in the additional information at the bottom of this page.

The system uses reversed phase chromatography with post column addition of sodium hydroxide for pulsed amperometric detection, except for the Kanamycin/Amikacin, which uses ion exchange chromatography. The supplied FlexCell with its easy exchangeable electrode guarantees for fast and user-friendly operation.

Application notes

 

Name
Doc#
Size
Download
Amikacin and Kanamycin according USP
217_015_15
0.69 MB
Amikacin sulfate according EP
217_043_06
1.17 MB
Azithromycin according USP
217_040_06
1.25 MB
Azithromycin_Erythromycin_Macrolide_Antibiotics
217_017_15
1.02 MB
Erythromycin ointments according USP
217_041_06
0.95 MB
Gentamicin EP USP
217_030_08
8.53 MB
Gentamicin Sulphate in Pharmaceuticals
217_013_17
0.62 MB
Neomycin and Framycetin Sulfate in bulk drugs
217_010_15
3.00 MB
Netilmicin sulphate according EP
217_031_11
0.85 MB
Spectinomycin and Lincomycin
217_019_11
0.86 MB
Spectinomycin in Pharmaceuticals
217_018_13
3.86 MB
Streptomycin Sulfate USP
217_036_06
0.68 MB
Sulfamethoxazole and Trimethoprim
217_042_04
0.72 MB
Tobramycin according EP
217_032_07
2.32 MB
Tobramycin in Pharmaceuticals
217_014_12
2.55 MB

EP/USP adjustments

 

Name
Doc#
Size
Download
Adjustment the USP Way
217_000_01
1.77 MB
Adjustment to USP Monographs Flexibility and Limitations
217_000_01
0.14 MB
Allowable_Compendial_Adjustments_LCGC
217_000_01
4.93 MB