Glutathione and disulfides
Glutathione and other sulfides
- Both mono- and disulfides in one run
- Single flow cell with diamond electrode, or
- Dual flow cell for selectivity with gold electrode
- Detection limits 2-10 (gold) or 25-100 nmol/L (diamond)
The Disulfides Analyzer has been developed for the analysis of (di-) sulfides such as (di-)glutathione, cystine, cysteine, homocystine, and homocysteine. The method applies a Flexcell with a Boron Doped Diamond working electrode for detection of mono and disulfides. Detection limits are below 0.1 µmol/L for most (di-)sulfides.
In an alternative setup a dual flowcell configuration is used with about 10 times better detection limit. The method uses an additional Flexcell for pre-reduction of di-thiols, a second cell is used for detection. If only the mono-sulfides are of interest, the Flexcell can be equipped with a Gold working electrode. This offers additional selectivity, and the lower working potential results in a better detection limit as well (10 nmol/L).
Neurotransmitter applications
| Title | Version | Size | Download |
|---|---|---|---|
| 211_004 - Glutathione, other Thiols, and Disulfides | 07 | 929.75 KB | Download |
| 221_253 - Fast analysis of Dopamine and Serotonin for high time resolution | 01 | 4.33 MB | Download |
| 211_005 - Aminothiols, Glutathione and disulfides | 02 | 545.38 KB | Download |
| 213_020 - GABA and glutamate | 12 | 1.74 MB | Download |
| 213_021 - Histamine | 03 | 408.04 KB | Download |
| 213_022 - Large Neutral Amino Acids | 01 | 507.15 KB | Download |
| 213_023 - Acetylcholine and Choline | 14 | 0.96 MB | Download |
| 213_028 - Monoamines and Metabolites | 09 | 1.17 MB | Download |
| 213_029 - OMD of neurotransmitters | 04 | 1.29 MB | Download |
| 213_030 - 3–Hydroxykynurenine | 02 | 444.02 KB | Download |
| 213_032 - Tyrosine, Tyramine and Octopamine | 01 | 353.84 KB | Download |