Glutathione and disulfides
Glutathione and other sulfides
- Both mono- and disulfides in one run
- Single flow cell with diamond electrode, or
- Dual flow cell for selectivity with gold electrode
- Detection limits 2-10 (gold) or 25-100 nmol/L (diamond)
The Disulfides Analyzer has been developed for the analysis of (di-) sulfides such as (di-)glutathione, cystine, cysteine, homocystine, and homocysteine. The method applies a Flexcell with a Boron Doped Diamond working electrode for detection of mono and disulfides. Detection limits are below 0.1 µmol/L for most (di-)sulfides.
In an alternative setup a dual flowcell configuration is used with about 10 times better detection limit. The method uses an additional Flexcell for pre-reduction of di-thiols, a second cell is used for detection. If only the mono-sulfides are of interest, the Flexcell can be equipped with a Gold working electrode. This offers additional selectivity, and the lower working potential results in a better detection limit as well (10 nmol/L).

Neurotransmitter applications
Title | Size | Download |
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211_004 - Glutathione, other Thiols, and Disulfides | 929.75 KB | DownloadPreview |
211_005 - Aminothiols, Glutathione and disulfides | 545.38 KB | DownloadPreview |
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213_028 - Monoamines and Metabolites | 1.17 MB | DownloadPreview |
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213_030 - 3–Hydroxykynurenine | 444.02 KB | DownloadPreview |
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