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ALEXYS Autosampler

AS

AS 110 - Fast and robust

 

 

 

The AS 110 is a new generation autosampler. It is a fast, robust and easy to use autosampler without compromising accuracy and reproducibility. The AS 110 includes indispensable features for the highest injection performance. It has a dual needle with positive headspace pressure, extensive wash routines for minimal carry over and 3 injection modes including µL pick-up mode for zero sample loss. In addition, the micro version of the AS has programmable injection routines called \'User Defined Programs\'.

The AS 110 can handle sample volumes down to 1 µL accurately and reproducibly. The sample tray offers temperature control down to 4°C. The fast needle movements result in unsurpassed speeds of less than 30s for a full cycle. These features make the AS 110 a perfect fit for high throughput routine analysis. The autosampler is available with a standard or UHPLC 6 port or 10 port valve (6-PV or 10-PV).


Product Flyers

  • AS110 - UHPLC Autosampler

Manuals

 

Part no Description
191.0035 Autosampler AS 110, cool, 6-PV
191.0037 Autosampler AS 110, cool, micro, 6-PV
191.0041 Autosampler AS 110, cool, 10-PV

UHPLC autosamplers:

Part no Description
191.0035U Autosampler AS 110, UHPLC, cool, 6-PV
191.0041U Autosampler AS 110, UHPLC, cool, 10-PV


26809614 - An improved microbore UHPLC method with electrochemicaldetection for the simultaneous determination of low monoaminelevels in in vivo brain microdialysis samples
Van Schoors J, Viaene J, Van Wanseele Y, Smolders I, Dejaegher B, Vander Heyden Y, Van Eeckhaut A; J Pharm Biomed Anal. 2016 Jan 13. pii: S0731-7085(16)30015-2

26116760 - Central serotonin2B receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow
Devroye C1, Cathala A2, Di Marco B3, Caraci F4, Drago F5, Piazza PV6, Spampinato U7.; Neuropharmacology. 2015 Oct;97:329-37. doi: 10.1016/j.neuropharm.2015.06.012. Epub 2015 Jun 25.

PMC3997604 - CCNP Heinz Lehmann Award Paper: Interference with AMPA receptor endocytosis: effects on behavioural and neurochemical correlates of amphetamine sensitization in male rats
Fiona Y. Choi, Soyon Ahn, Yu Tian Wang, Anthony G. Phillips; J Psychiatry Neurosci. 2014 May; 39(3): 189-199

PMC3898275 - Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P ?-synuclein BAC transgenic mouse
Tonya N. Taylor, Dawid Potgieter, Sabina Anwar, Steven L. Senior, Stephanie Janezic, Sarah Threlfell, Brent Ryan, Laura Parkkinen, Thierry Deltheil, Milena Cioroch, Achilleas Livieratos, Peter L. Oliver, Katie A. Jennings, Kay E. Davies, Olaf Ansorge, David M. Bannerman, Stephanie J. Cragg, Richard Wade-Martins; Neurobiol Dis. 2014 February; 62(100): 193-207

PMC3878764 - Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress
Nicoleta Moisoi, Valentina Fedele, Jennifer Edwards, L. Miguel Martins; Neuropharmacology. 2014 February; 77(100): 350-357

PMC4030331 - Locomotor hyperactivity in 14-3-3? KO mice is associated with dopamine transporter dysfunction
H Ramshaw, X Xu, E J Jaehne, P McCarthy, Z Greenberg, E Saleh, B McClure, J Woodcock, S Kabbara, S Wiszniak, Ting-Yi Wang, C Parish, M van den Buuse, B T Baune, A Lopez, Q Schwarz; Transl Psychiatry. 2013 December; 3(12): e327

PMC3633373 - Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited ?-synuclein accumulation and age-dependent sensorimotor deficits
Patrick J. Schultheis, Sheila M. Fleming, Amy K. Clippinger, Jada Lewis, Taiji Tsunemi, Benoit Giasson, Dennis W. Dickson, Joseph R. Mazzulli, Mark E. Bardgett, Kristi L. Haik, Osunde Ekhator, Anil Kumar Chava, John Howard, Matt Gannon, Elizabeth Hoffman, Yinhuai Chen, Vikram Prasad, Stephen C. Linn, Rafael J. Tamargo, Wendy Westbroek, Ellen Sidransky, Dimitri Krainc, Gary E. Shull; Hum Mol Genet. 2013 May 15; 22(10): 2067-2082

PMC3678035 - A functional role for both ?-aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus
Flavie Kersante, Samuel C S Rowley, Ivan Pavlov, Maria Guticrrez-Mecinas, Alexey Semyanov, Johannes M H M Reul, Matthew C Walker, Astrid C E Linthorst; J Physiol. 2013 May 15; 591(Pt 10): 2429-2441

PMC3676285 - Intravenous Ethanol Increases Extracellular Dopamine in the Medial Prefrontal Cortex of the Long-Evans Rat
Christina J. Schier, Geoffrey A. Dilly, Rueben A. Gonzales; Alcohol Clin Exp Res. 2013 May; 37(5): 740-747

PMC3574236 - Paradoxical effects of low dose MDMA on latent inhibition in the rat
A.J.D. Nelson, K.E. Thur, C.A. Marsden, H.J. Cassaday; Neuropharmacology. 2013 April; 67(C): 331-336

PMC3645893 - Dopamine and its metabolites in cathepsin D heterozygous mice before and after MPTP administration
Donna Crabtree, Michael Boyer-Guittaut, Xiaosen Ouyang, Naomi Fineberg, Jianhua Zhang; Neurosci Lett. 2013 March 22; 538: 3-8.

PMC3591781 - GABA-independent GABAA Receptor Openings Maintain Tonic Currents
Agnieszka I. Wlodarczyk, Sergiy Sylantyev, Murray B. Herd, Flavie Kersante, Jeremy J. Lambert, Dmitri A. Rusakov, Astrid C.E. Linthorst, Alexey Semyanov, Delia Belelli, Ivan Pavlov, Matthew C. Walker; J Neurosci. 2013 February 27; 33(9): 3905-3914.

PMC3567364 - Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone
George Gallos, Elizabeth Townsend, Peter Yim, Laszlo Virag, Yi Zhang, Dingbang Xu, Matthew Bacchetta, Charles W. Emala; Am J Physiol Lung Cell Mol Physiol. 2013 February 1; 304(3): L191-L197

PMC3631384 - Differential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone-induced hypothermia
SE Shortall, AR Green, KM Swift, KCF Fone, MV King; Br J Pharmacol. 2013 February; 168(4): 966-977

PMC3572936 - A progressive dopaminergic phenotype associated with neurotoxic conversion of ?-synuclein in BAC-transgenic rats
Silke Nuber, Florian Harmuth, Zacharias Kohl, Anthony Adame, Margaritha Trejo, Kai Schonig, Frank Zimmermann, Claudia Bauer, Nicolas Casadei, Christiane Giel, Carsten Calaminus, Bernd J. Pichler, Poul H. Jensen, Christian P. Muller, Davide Amato, Johannes Kornhuber, Peter Teismann, Hodaka Yamakado, Ryosuke Takahashi, Juergen Winkler, Eliezer Masliah, Olaf Riess; Brain. 2013 February; 136(2): 412-432

PMC3545765 - Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
Arthur G. Fitzmaurice, Shannon L. Rhodes, Aaron Lulla, Niall P. Murphy, Hoa A. Lam, Kelley C. ODonnell, Lisa Barnhill, John E. Casida, Myles Cockburn, Alvaro Sagasti, Mark C. Stahl, Nigel T. Maidment, Beate Ritz, Jeff M. Bronstein; Proc Natl Acad Sci U S A. 2013 January 8; 110(2): 636-641

PMC3556740 - Inhibition of pre-ischeamic conditioning in the mouse caudate brain slice by NMDA- or adenosine A1 receptor antagonists
Nikky K. Chauhan, Andrew M.J. Young, Claire L. Gibson, Colin Davidson; Eur J Pharmacol. 2013 January 5; 698(1-3): 322-329

PMC3527243 - Dispensable, Redundant, Complementary, and Cooperative Roles of Dopamine, Octopamine, and Serotonin in Drosophila melanogaster
Audrey Chen, Fanny Ng, Tim Lebestky, Anna Grygoruk, Christine Djapri, Hakeem O. Lawal, Harshul A. Zaveri, Filmon Mehanzel, Rod Najibi, Gabriel Seidman, Niall P. Murphy, Rachel L. Kelly, Larry C. Ackerson, Nigel T. Maidment, F. Rob Jackson, David E. Krantz; Genetics. 2013 January; 193(1): 159-176

PMC3502677 - Electrophilic Adduction of Ubiquitin Activating Enzyme E1 by N,N-Diethyldithiocarbamate Inhibits Ubiquitin Activation and is Accompanied by Striatal Injury in the Rat
Olga M. Viquez, Samuel W. Caito, W. Hayes McDonald, David B. Friedman, William M. Valentine; Chem Res Toxicol. 2012 November 19; 25(11): 2310-2321

23642417 - Analysis of Glutamate, GABA, Noradrenaline, Dopamine, Serotonin and Metabolites using microbore UHPLC with Electrochemical Detection.
Reinhoud NJ, Brouwer HJ, van Heerwaarden LM, Korte-Bouws GA.; ACS Chem Neurosci. 2013 May 3. [Epub ahead of print]

23300984 - IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates.
Aron Badin R, Spinnewyn B, Gaillard MC, Jan C, Malgorn C, Van Camp N, Dollé F, Guillermier M, Boulet S, Bertrand A, Savasta M, Auguet M, Brouillet E, Chabrier PE, Hantraye P.; PLoS One. 2013;8(1):e52680. doi: 10.1371/journal.pone.0052680. Epub 2013 Jan 3.

23228189 - Marine omega-3 polyunsaturated fatty acids induce sex-specific changes in reinforcer-controlled behaviour and neurotransmitter metabolism in a spontaneously hypertensive rat model of ADHD.
Dervola KS, Roberg BA, Wøien G, Bogen IL, Sandvik TH, Sagvolden T, Drevon CA, Johansen EB, Walaas SI.; Behav Brain Funct. 2012 Dec 10;8:56. doi: 10.1186/1744-9081-8-56.

23201353 - Paradoxical effects of low dose MDMA on latent inhibition in the rat.
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23166710 - Concomitant release of ventral tegmental acetylcholine and accumbal dopamine by ghrelin in rats.
Jerlhag E, Janson AC, Waters S, Engel JA.; PLoS One. 2012;7(11):e49557. doi: 10.1371/journal.pone.0049557. Epub 2012 Nov 14.

23099254 - Inhibition of pre-ischeamic conditioning in the mouse caudate brain slice by NMDA- or adenosine A1 receptor antagonists.
Chauhan NK, Young AM, Gibson CL, Davidson C.; Eur J Pharmacol. 2013 Jan 5;698(1-3):322-9. doi: 10.1016/j.ejphar.2012.10.021. Epub 2012 Oct 23.

23077667 - Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels.
Lambertsen KL, Gramsbergen JB, Sivasaravanaparan M, Ditzel N, Sevelsted-Møller LM, Oliván-Viguera A, Rabjerg M, Wulff H, Köhler R.; PLoS One. 2012;7(10):e47744. doi: 10.1371/journal.pone.0047744. Epub 2012 Oct 15.

23029034 - Mephedrone in adolescent rats: residual memory impairment and acute but not lasting 5-HT depletion.
Motbey CP, Karanges E, Li KM, Wilkinson S, Winstock AR, Ramsay J, Hicks C, Kendig MD, Wyatt N, Callaghan PD, McGregor IS.; PLoS One. 2012;7(9):e45473. doi: 10.1371/journal.pone.0045473. Epub 2012 Sep 18.

22916173 - Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1Î?.
Lucas EK, Dougherty SE, McMeekin LJ, Trinh AT, Reid CS, Cowell RM.; PLoS One. 2012;7(8):e42878. doi: 10.1371/journal.pone.0042878. Epub 2012 Aug 14.

22908044 - Forward genetic analysis to identify determinants of dopamine signaling in Caenorhabditis elegans using swimming-induced paralysis.
Hardaway JA, Hardie SL, Whitaker SM, Baas SR, Zhang B, Bermingham DP, Lichtenstein AJ, Blakely RD.; G3 (Bethesda). 2012 Aug;2(8):961-75. doi: 10.1534/g3.112.003533. Epub 2012 Aug 1.

22864020 - Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice.
Zurkovsky L, Bychkov E, Tsakem EL, Siedlecki C, Blakely RD, Gurevich EV.; Dis Model Mech. 2013 Jan;6(1):171-83. doi: 10.1242/dmm.010363. Epub 2012 Aug 3.

22815336 - Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition.
Laatikainen LM, Sharp T, Bannerman DM, Harrison PJ, Tunbridge EM.; J Psychopharmacol. 2012 Dec;26(12):1561-8. doi: 10.1177/0269881112454228. Epub 2012 Jul 19.

22737024 - Electrochemical oxidation of cysteine at a film gold modified carbon fiber microelectrode its application in a flow-through voltammetric sensor.
Wang LH, Huang WS.; Sensors (Basel). 2012;12(3):3562-77. doi: 10.3390/s120303562. Epub 2012 Mar 14.

22723923 - PET imaging a MPTP-induced mouse model of Parkinson's disease using the fluoropropyl-dihydrotetrabenazine analog [18F]-DTBZ (AV-133).
Toomey JS, Bhatia S, Moon LT, Orchard EA, Tainter KH, Lokitz SJ, Terry T, Mathis JM, Penman AD.; PLoS One. 2012;7(6):e39041. doi: 10.1371/journal.pone.0039041. Epub 2012 Jun 18.

22454087 - Mechanism-based pharmacokinetic/pharmacodynamic modeling of rat prefrontal cortical dopamine response to dual acting norepinephrine reuptake inhibitor and 5-HT1A partial agonist.
Li CS, Zhang L, Haske T, Dounay A, Gray D, Barta N, Brodfuehrer J, Lepsy C, Campbell B.; AAPS J. 2012 Jun;14(2):365-76. doi: 10.1208/s12248-012-9343-8. Epub 2012 Mar 28.

22447154 - In vivo catecholaminergic metabolism in the medial prefrontal cortex of ENU2 mice: an investigation of the cortical dopamine deficit in phenylketonuria.
Pascucci T, Giacovazzo G, Andolina D, Conversi D, Cruciani F, Cabib S, Puglisi-Allegra S.; J Inherit Metab Dis. 2012 Nov;35(6):1001-9. doi: 10.1007/s10545-012-9473-2. Epub 2012 Mar 24.

22363697 - Role of Chd7 in zebrafish: a model for CHARGE syndrome.
Patten SA, Jacobs-McDaniels NL, Zaouter C, Drapeau P, Albertson RC, Moldovan F.; PLoS One. 2012;7(2):e31650. doi: 10.1371/journal.pone.0031650. Epub 2012 Feb 20.

22330650 - A rat model of diabetic wound infection for the evaluation of topical antimicrobial therapies.
Mendes JJ, Leandro CI, Bonaparte DP, Pinto AL.; Comp Med. 2012 Feb;62(1):37-48.

22316420 - Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease.
Ravenstijn PG, Drenth HJ, O'Neill MJ, Danhof M, de Lange EC.; Fluids Barriers CNS. 2012 Feb 8;9:4. doi: 10.1186/2045-8118-9-4.

22244974 - Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats.
Ehrlich D, Pirchl M, Humpel C.; Neuroscience. 2012 Mar 15;205:154-66. doi: 10.1016/j.neuroscience.2011.12.054. Epub 2012 Jan 5.

22214848 - Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia.
Lee HY, Nakayama J, Xu Y, Fan X, Karouani M, Shen Y, Pothos EN, Hess EJ, Fu YH, Edwards RH, Ptácek LJ.; J Clin Invest. 2012 Feb 1;122(2):507-18. doi: 10.1172/JCI58470. Epub 2012 Jan 3.

22032926 - Glucocorticoid receptors in the prefrontal cortex regulate stress-evoked dopamine efflux and aspects of executive function.
Butts KA, Weinberg J, Young AH, Phillips AG.; Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18459-64. doi: 10.1073/pnas.1111746108. Epub 2011 Oct 27.

22015977 - Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
Duszczyk-Budhathoki M, Olczak M, Lehner M, Majewska MD.; Neurochem Res. 2012 Feb;37(2):436-47. doi: 10.1007/s11064-011-0630-z. Epub 2011 Oct 21.

21957162 - Rate of fall in blood glucose and recurrent hypoglycemia affect glucose dynamics and noradrenergic activation in the ventromedial hypothalamus.
Barnes MB, Lawson MA, Beverly JL.; Am J Physiol Regul Integr Comp Physiol. 2011 Dec;301(6):R1815-20. doi: 10.1152/ajpregu.00171.2011. Epub 2011 Sep 28.

21951066 - The oxysterol 27-hydroxycholesterol regulates Î?-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease.
Marwarha G, Rhen T, Schommer T, Ghribi O.; J Neurochem. 2011 Dec;119(5):1119-36. doi: 10.1111/j.1471-4159.2011.07497.x. Epub 2011 Oct 24.

21871902 - L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease.
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21745564 - Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity.
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21615684 - Altered ADAR 2 equilibrium and 5HT(2C) R editing in the prefrontal cortex of ADAR 2 transgenic mice.
Singh M, Singh MM, Na E, Agassandian K, Zimmerman MB, Johnson AK.; Genes Brain Behav. 2011 Aug;10(6):637-47. doi: 10.1111/j.1601-183X.2011.00701.x. Epub 2011 Jun 13.

21609470 - Biogenic amines and their metabolites are differentially affected in the Mecp2-deficient mouse brain.
Panayotis N, Ghata A, Villard L, Roux JC.; BMC Neurosci. 2011 May 24;12:47. doi: 10.1186/1471-2202-12-47.

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Anwar S, Peters O, Millership S, Ninkina N, Doig N, Connor-Robson N, Threlfell S, Kooner G, Deacon RM, Bannerman DM, Bolam JP, Chandra SS, Cragg SJ, Wade-Martins R, Buchman VL.; J Neurosci. 2011 May 18;31(20):7264-74. doi: 10.1523/JNEUROSCI.6194-10.2011.

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Shelkovnikova TA, Ustyugov AA, Millership S, Peters O, Anichtchik O, Spillantini MG, Buchman VL, Bachurin SO, Ninkina NN.; Neurodegener Dis. 2011;8(6):430-7. doi: 10.1159/000324989. Epub 2011 May 12.

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Byrnes JJ, Gleason ED, Schoen MT, Lovelock DF, Carini LM, Byrnes EM, Bridges RS.; Behav Brain Res. 2011 Oct 1;223(2):322-8. doi: 10.1016/j.bbr.2011.04.048. Epub 2011 May 6.

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Justin GA, Zhang Y, Cui XT, Bradberry CW, Sun M, Sclabassi RJ.; J Biol Eng. 2011 May 10;5:5. doi: 10.1186/1754-1611-5-5.

21557885 - Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli.
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21408191 - Progressive neurodegeneration or endogenous compensation in an animal model of Parkinson's disease produced by decreasing doses of alpha-synuclein.
Koprich JB, Johnston TH, Huot P, Reyes MG, Espinosa M, Brotchie JM.; PLoS One. 2011 Mar 7;6(3):e17698. doi: 10.1371/journal.pone.0017698.

21383081 - Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model.
Choi WS, Palmiter RD, Xia Z.; J Cell Biol. 2011 Mar 7;192(5):873-82. doi: 10.1083/jcb.201009132.

21262855 - Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; J Psychopharmacol. 2011 Dec;25(12):1649-60. doi: 10.1177/0269881110389211. Epub 2011 Jan 24.

21209205 - Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioning.
Ostlund SB, Wassum KM, Murphy NP, Balleine BW, Maidment NT.; J Neurosci. 2011 Jan 5;31(1):200-7. doi: 10.1523/JNEUROSCI.4759-10.2011.

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Nunes T, Rocha JF, Vaz-da-Silva M, Igreja B, Wright LC, Falc?o A, Almeida L, Soares-da-Silva P.; Drugs R D. 2010;10(4):225-42. doi: 10.2165/11586310-000000000-00000.

21152205 - Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression-An Animal Model Study.
Malkesman O, Asaf T, Shbiro L, Goldstein A, Maayan R, Weizman A, Kinor N, Okun E, Sredni B, Yadid G, Weller A.; Adv Pharmacol Sci. 2009;2009:405107. doi: 10.1155/2009/405107. Epub 2009 Oct 18.

21133535 - Dissociable roles of dopamine within the core and medial shell of the nucleus accumbens in memory for objects and place.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; Behav Neurosci. 2010 Dec;124(6):789-99. doi: 10.1037/a0021114.

21042794 - Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice.
Cassano T, Gaetani S, Macheda T, Laconca L, Romano A, Morgese MG, Cimmino CS, Chiarotti F, Bambico FR, Gobbi G, Cuomo V, Piomelli D.; Psychopharmacology (Berl). 2011 Mar;214(2):465-76. doi: 10.1007/s00213-010-2051-0. Epub 2010 Nov 2.

20981353 - Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice.
Hurko O, Boudonck K, Gonzales C, Hughes ZA, Jacobsen JS, Reinhart PH, Crowther D.; Int J Alzheimers Dis. 2010 Oct 11;2010:864625. doi: 10.4061/2010/864625.

20934452 - The potential and limitations of DOV 216,303 as a triple reuptake inhibitor for the treatment of major depression: a microdialysis study in olfactory bulbectomized rats.
Prins J, Westphal KG, Korte-Bouws GA, Quinton MS, Schreiber R, Olivier B, Korte SM.; Pharmacol Biochem Behav. 2011 Jan;97(3):444-52. doi: 10.1016/j.pbb.2010.10.001. Epub 2010 Oct 8.

20934393 - Biogenic amines and their metabolites in mouse brain tissue: development, optimization and validation of an analytical HPLC method.
Nguyen AT, Aerts T, Van Dam D, De Deyn PP.; J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Nov 1;878(29):3003-14. doi: 10.1016/j.jchromb.2010.09.019. Epub 2010 Sep 29.

20864506 - The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties.
Caldarone BJ, Paterson NE, Zhou J, Brunner D, Kozikowski AP, Westphal KG, Korte-Bouws GA, Prins J, Korte SM, Olivier B, Ghavami A.; J Pharmacol Exp Ther. 2010 Dec;335(3):762-70. doi: 10.1124/jpet.110.174011. Epub 2010 Sep 23.

20844316 - Adult-onset, short-term dietary restriction reduces cell senescence in mice.
Wang C, Maddick M, Miwa S, Jurk D, Czapiewski R, Saretzki G, Langie SA, Godschalk RW, Cameron K, von Zglinicki T.; Aging (Albany NY). 2010 Sep;2(9):555-66.

20739551 - Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis.
Robertson SD, Matthies HJ, Owens WA, Sathananthan V, Christianson NS, Kennedy JP, Lindsley CW, Daws LC, Galli A.; J Neurosci. 2010 Aug 25;30(34):11305-16. doi: 10.1523/JNEUROSCI.0126-10.2010.

20649591 - Preferential in vivo action of F15599, a novel 5-HT(1A) receptor agonist, at postsynaptic 5-HT(1A) receptors.
Llad?-Pelfort L, Assié MB, Newman-Tancredi A, Artigas F, Celada P.; Br J Pharmacol. 2010 Aug;160(8):1929-40. doi: 10.1111/j.1476-5381.2010.00738.x.

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Austin PJ, Betts MJ, Broadstock M, O'Neill MJ, Mitchell SN, Duty S.; Br J Pharmacol. 2010 Aug;160(7):1741-53. doi: 10.1111/j.1476-5381.2010.00820.x.

20619321 - Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; Neuroscience. 2010 Sep 29;170(1):99-106. doi: 10.1016/j.neuroscience.2010.06.066. Epub 2010 Jul 7.

20615977 - Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA-induced dyskinesia in rats.
Ulusoy A, Sahin G, Kirik D.; Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13159-64. doi: 10.1073/pnas.1003432107. Epub 2010 Jul 6.

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