Heparin
Heparin analysis
- U.S. Pharmacopeia 37NF32 (2014)
- Analysis of galactosamine impurities in heparin
- Reproducible & robust
Heparin is a highly sulfated glycosaminoglycan widely used as an injectable anti-coagulant. After a major incident in March 2008 with contaminated heparin, the USP revised the heparin monograph to detect possible impurities. High Performance Anion Exchange Chromatography followed by Pulsed Amperometric Detection is used to check for the presence of galactosamine in hydrolyzed heparin samples. The method has been evaluated using an ALEXYS Analyzer, to demonstrate the system performance.
