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ALEXYS Analyzers


UHPLC with electrochemical detection



The ALEXYS is a HPLC system with electrochemical detection that has been designed to meet the highest demands for detection sensitivity and performance. The ALEXYS is easily upgradeable to micro-bore and capillary LC-EC. The system uses Clarity, a fully featured data acquisition software with all the tools for automated data acquisition, calibration, processing and reporting.

An ALEXYS analyzer additionally has the appropriate kit that is optimized for a specific application. For example, guaranteed applications have been developed for the analysis of neurotransmitters such as noradrenaline, dopamine, serotonin and metabolites in microdialysates. Typically, picomolar concentration detection limits have been obtained in only a few microliters of sample. Parallel detection schemes using multiple flow cells have been developed for time, sample and experimental cost savings! The ALEXYS has proven its performance in routine analysis in clinical, food & beverage, environmental and pharmaceutical laboratories as well. For more information download a brochure, or contact us for a quote or any other questions.


Applications:<br>Analyzers & Detectors


ALEXYS Autosampler

Product Flyers


Part no.
180.0035W ALEXYS Cool
180.0037W ALEXYS Cool, Micro
180.0039W ALEXYS Clinical Analyzer
180.0050W ALEXYS Aminoglycosides Analyzer
180.0053WM ALEXYS FDG Analyzer
180.0054W ALEXYS Carbohydrates Analyzer
180.0056W ALEXYS Gentamicin Analyzer
180.0058W ALEXYS Kanamycin/Amikacin Analyzer
180.0059W ALEXYS Spectinomycin/Lincomycin Analyzer
180.0068W ALEXYS Disulfides Analyzer
180.0069W ALEXYS Disulfides Analyzer, BDD
180.0081W ALEXYS OMD monoamines Analyzer
180.0082W ALEXYS OMD High Throughput
180.0083W ALEXYS OMD Time Resolution
180.0086W ALEXYS Macrolide Antibiotics Analyzer
180.0091W ALEXYS Neurotransmitters BP, 1 ch
180.0091WM ALEXYS Neurotransmitters BP manual injector, 1 ch
180.0092W ALEXYS Neurotransmitters BP, 2 ch
180.0094W ALEXYS Polyphenols Analyzer

Contact us for a quote or any other questions.

2019001 - Behavioural and Neurochemical Assessment of Heantos 4 on Preclinical Models of Morphine-Dependence
Carine Dias, Soyon Ahn, Bonita Ma, Tran Van Sung˙and Anthony G Phillips; Journal of Addiction Research & Therapy

26809614 - An improved microbore UHPLC method with electrochemicaldetection for the simultaneous determination of low monoaminelevels in in vivo brain microdialysis samples
Van Schoors J, Viaene J, Van Wanseele Y, Smolders I, Dejaegher B, Vander Heyden Y, Van Eeckhaut A; J Pharm Biomed Anal. 2016 Jan 13. pii: S0731-7085(16)30015-2

26116760 - Central serotonin2B receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow
Devroye C1, Cathala A2, Di Marco B3, Caraci F4, Drago F5, Piazza PV6, Spampinato U7.; Neuropharmacology.˙2015 Oct;97:329-37. doi: 10.1016/j.neuropharm.2015.06.012. Epub 2015 Jun 25.

PMC3997604 - CCNP Heinz Lehmann Award Paper: Interference with AMPA receptor endocytosis: effects on behavioural and neurochemical correlates of amphetamine sensitization in male rats
Fiona Y. Choi, Soyon Ahn, Yu Tian Wang, Anthony G. Phillips; J Psychiatry Neurosci. 2014 May; 39(3): 189-199

PMC3898275 - Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P ?-synuclein BAC transgenic mouse
Tonya N. Taylor, Dawid Potgieter, Sabina Anwar, Steven L. Senior, Stephanie Janezic, Sarah Threlfell, Brent Ryan, Laura Parkkinen, Thierry Deltheil, Milena Cioroch, Achilleas Livieratos, Peter L. Oliver, Katie A. Jennings, Kay E. Davies, Olaf Ansorge, David M. Bannerman, Stephanie J. Cragg, Richard Wade-Martins; Neurobiol Dis. 2014 February; 62(100): 193-207

PMC3878764 - Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress
Nicoleta Moisoi, Valentina Fedele, Jennifer Edwards, L. Miguel Martins; Neuropharmacology. 2014 February; 77(100): 350-357

PMC4030331 - Locomotor hyperactivity in 14-3-3? KO mice is associated with dopamine transporter dysfunction
H Ramshaw, X Xu, E J Jaehne, P McCarthy, Z Greenberg, E Saleh, B McClure, J Woodcock, S Kabbara, S Wiszniak, Ting-Yi Wang, C Parish, M van den Buuse, B T Baune, A Lopez, Q Schwarz; Transl Psychiatry. 2013 December; 3(12): e327

PMC3633373 - Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited ?-synuclein accumulation and age-dependent sensorimotor deficits
Patrick J. Schultheis, Sheila M. Fleming, Amy K. Clippinger, Jada Lewis, Taiji Tsunemi, Benoit Giasson, Dennis W. Dickson, Joseph R. Mazzulli, Mark E. Bardgett, Kristi L. Haik, Osunde Ekhator, Anil Kumar Chava, John Howard, Matt Gannon, Elizabeth Hoffman, Yinhuai Chen, Vikram Prasad, Stephen C. Linn, Rafael J. Tamargo, Wendy Westbroek, Ellen Sidransky, Dimitri Krainc, Gary E. Shull; Hum Mol Genet. 2013 May 15; 22(10): 2067-2082

PMC3678035 - A functional role for both ?-aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus
Flavie Kersante, Samuel C S Rowley, Ivan Pavlov, Maria Guticrrez-Mecinas, Alexey Semyanov, Johannes M H M Reul, Matthew C Walker, Astrid C E Linthorst; J Physiol. 2013 May 15; 591(Pt 10): 2429-2441

PMC3676285 - Intravenous Ethanol Increases Extracellular Dopamine in the Medial Prefrontal Cortex of the Long-Evans Rat
Christina J. Schier, Geoffrey A. Dilly, Rueben A. Gonzales; Alcohol Clin Exp Res. 2013 May; 37(5): 740-747

PMC3574236 - Paradoxical effects of low dose MDMA on latent inhibition in the rat
A.J.D. Nelson, K.E. Thur, C.A. Marsden, H.J. Cassaday; Neuropharmacology. 2013 April; 67(C): 331-336

PMC3645893 - Dopamine and its metabolites in cathepsin D heterozygous mice before and after MPTP administration
Donna Crabtree, Michael Boyer-Guittaut, Xiaosen Ouyang, Naomi Fineberg, Jianhua Zhang; Neurosci Lett. 2013 March 22; 538: 3-8.

PMC3591781 - GABA-independent GABAA Receptor Openings Maintain Tonic Currents
Agnieszka I. Wlodarczyk, Sergiy Sylantyev, Murray B. Herd, Flavie Kersante, Jeremy J. Lambert, Dmitri A. Rusakov, Astrid C.E. Linthorst, Alexey Semyanov, Delia Belelli, Ivan Pavlov, Matthew C. Walker; J Neurosci. 2013 February 27; 33(9): 3905-3914.

PMC3567364 - Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone
George Gallos, Elizabeth Townsend, Peter Yim, Laszlo Virag, Yi Zhang, Dingbang Xu, Matthew Bacchetta, Charles W. Emala; Am J Physiol Lung Cell Mol Physiol. 2013 February 1; 304(3): L191-L197

PMC3631384 - Differential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone-induced hypothermia
SE Shortall, AR Green, KM Swift, KCF Fone, MV King; Br J Pharmacol. 2013 February; 168(4): 966-977

PMC3572936 - A progressive dopaminergic phenotype associated with neurotoxic conversion of ?-synuclein in BAC-transgenic rats
Silke Nuber, Florian Harmuth, Zacharias Kohl, Anthony Adame, Margaritha Trejo, Kai Schonig, Frank Zimmermann, Claudia Bauer, Nicolas Casadei, Christiane Giel, Carsten Calaminus, Bernd J. Pichler, Poul H. Jensen, Christian P. Muller, Davide Amato, Johannes Kornhuber, Peter Teismann, Hodaka Yamakado, Ryosuke Takahashi, Juergen Winkler, Eliezer Masliah, Olaf Riess; Brain. 2013 February; 136(2): 412-432

PMC3545765 - Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease
Arthur G. Fitzmaurice, Shannon L. Rhodes, Aaron Lulla, Niall P. Murphy, Hoa A. Lam, Kelley C. ODonnell, Lisa Barnhill, John E. Casida, Myles Cockburn, Alvaro Sagasti, Mark C. Stahl, Nigel T. Maidment, Beate Ritz, Jeff M. Bronstein; Proc Natl Acad Sci U S A. 2013 January 8; 110(2): 636-641

PMC3556740 - Inhibition of pre-ischeamic conditioning in the mouse caudate brain slice by NMDA- or adenosine A1 receptor antagonists
Nikky K. Chauhan, Andrew M.J. Young, Claire L. Gibson, Colin Davidson; Eur J Pharmacol. 2013 January 5; 698(1-3): 322-329

PMC3527243 - Dispensable, Redundant, Complementary, and Cooperative Roles of Dopamine, Octopamine, and Serotonin in Drosophila melanogaster
Audrey Chen, Fanny Ng, Tim Lebestky, Anna Grygoruk, Christine Djapri, Hakeem O. Lawal, Harshul A. Zaveri, Filmon Mehanzel, Rod Najibi, Gabriel Seidman, Niall P. Murphy, Rachel L. Kelly, Larry C. Ackerson, Nigel T. Maidment, F. Rob Jackson, David E. Krantz; Genetics. 2013 January; 193(1): 159-176

PMC3502677 - Electrophilic Adduction of Ubiquitin Activating Enzyme E1 by N,N-Diethyldithiocarbamate Inhibits Ubiquitin Activation and is Accompanied by Striatal Injury in the Rat
Olga M. Viquez, Samuel W. Caito, W. Hayes McDonald, David B. Friedman, William M. Valentine; Chem Res Toxicol. 2012 November 19; 25(11): 2310-2321

23642417 - Analysis of Glutamate, GABA, Noradrenaline, Dopamine, Serotonin and Metabolites using microbore UHPLC with Electrochemical Detection.
Reinhoud NJ, Brouwer HJ, van Heerwaarden LM, Korte-Bouws GA.; ACS Chem Neurosci. 2013 May 3. [Epub ahead of print]

23300984 - IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates.
Aron Badin R, Spinnewyn B, Gaillard MC, Jan C, Malgorn C, Van Camp N, Doll‚ F, Guillermier M, Boulet S, Bertrand A, Savasta M, Auguet M, Brouillet E, Chabrier PE, Hantraye P.; PLoS One. 2013;8(1):e52680. doi: 10.1371/journal.pone.0052680. Epub 2013 Jan 3.

23228189 - Marine omega-3 polyunsaturated fatty acids induce sex-specific changes in reinforcer-controlled behaviour and neurotransmitter metabolism in a spontaneously hypertensive rat model of ADHD.
Dervola KS, Roberg BA, W›ien G, Bogen IL, Sandvik TH, Sagvolden T, Drevon CA, Johansen EB, Walaas SI.; Behav Brain Funct. 2012 Dec 10;8:56. doi: 10.1186/1744-9081-8-56.

23201353 - Paradoxical effects of low dose MDMA on latent inhibition in the rat.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; Neuropharmacology. 2013 Apr;67:331-6. doi: 10.1016/j.neuropharm.2012.11.012. Epub 2012 Nov 29.

23166710 - Concomitant release of ventral tegmental acetylcholine and accumbal dopamine by ghrelin in rats.
Jerlhag E, Janson AC, Waters S, Engel JA.; PLoS One. 2012;7(11):e49557. doi: 10.1371/journal.pone.0049557. Epub 2012 Nov 14.

23099254 - Inhibition of pre-ischeamic conditioning in the mouse caudate brain slice by NMDA- or adenosine A1 receptor antagonists.
Chauhan NK, Young AM, Gibson CL, Davidson C.; Eur J Pharmacol. 2013 Jan 5;698(1-3):322-9. doi: 10.1016/j.ejphar.2012.10.021. Epub 2012 Oct 23.

23077667 - Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels.
Lambertsen KL, Gramsbergen JB, Sivasaravanaparan M, Ditzel N, Sevelsted-M›ller LM, Oliv n-Viguera A, Rabjerg M, Wulff H, K”hler R.; PLoS One. 2012;7(10):e47744. doi: 10.1371/journal.pone.0047744. Epub 2012 Oct 15.

23029034 - Mephedrone in adolescent rats: residual memory impairment and acute but not lasting 5-HT depletion.
Motbey CP, Karanges E, Li KM, Wilkinson S, Winstock AR, Ramsay J, Hicks C, Kendig MD, Wyatt N, Callaghan PD, McGregor IS.; PLoS One. 2012;7(9):e45473. doi: 10.1371/journal.pone.0045473. Epub 2012 Sep 18.

22916173 - Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1×?.
Lucas EK, Dougherty SE, McMeekin LJ, Trinh AT, Reid CS, Cowell RM.; PLoS One. 2012;7(8):e42878. doi: 10.1371/journal.pone.0042878. Epub 2012 Aug 14.

22908044 - Forward genetic analysis to identify determinants of dopamine signaling in Caenorhabditis elegans using swimming-induced paralysis.
Hardaway JA, Hardie SL, Whitaker SM, Baas SR, Zhang B, Bermingham DP, Lichtenstein AJ, Blakely RD.; G3 (Bethesda). 2012 Aug;2(8):961-75. doi: 10.1534/g3.112.003533. Epub 2012 Aug 1.

22864020 - Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice.
Zurkovsky L, Bychkov E, Tsakem EL, Siedlecki C, Blakely RD, Gurevich EV.; Dis Model Mech. 2013 Jan;6(1):171-83. doi: 10.1242/dmm.010363. Epub 2012 Aug 3.

22815336 - Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition.
Laatikainen LM, Sharp T, Bannerman DM, Harrison PJ, Tunbridge EM.; J Psychopharmacol. 2012 Dec;26(12):1561-8. doi: 10.1177/0269881112454228. Epub 2012 Jul 19.

22737024 - Electrochemical oxidation of cysteine at a film gold modified carbon fiber microelectrode its application in a flow-through voltammetric sensor.
Wang LH, Huang WS.; Sensors (Basel). 2012;12(3):3562-77. doi: 10.3390/s120303562. Epub 2012 Mar 14.

22723923 - PET imaging a MPTP-induced mouse model of Parkinson's disease using the fluoropropyl-dihydrotetrabenazine analog [18F]-DTBZ (AV-133).
Toomey JS, Bhatia S, Moon LT, Orchard EA, Tainter KH, Lokitz SJ, Terry T, Mathis JM, Penman AD.; PLoS One. 2012;7(6):e39041. doi: 10.1371/journal.pone.0039041. Epub 2012 Jun 18.

22454087 - Mechanism-based pharmacokinetic/pharmacodynamic modeling of rat prefrontal cortical dopamine response to dual acting norepinephrine reuptake inhibitor and 5-HT1A partial agonist.
Li CS, Zhang L, Haske T, Dounay A, Gray D, Barta N, Brodfuehrer J, Lepsy C, Campbell B.; AAPS J. 2012 Jun;14(2):365-76. doi: 10.1208/s12248-012-9343-8. Epub 2012 Mar 28.

22447154 - In vivo catecholaminergic metabolism in the medial prefrontal cortex of ENU2 mice: an investigation of the cortical dopamine deficit in phenylketonuria.
Pascucci T, Giacovazzo G, Andolina D, Conversi D, Cruciani F, Cabib S, Puglisi-Allegra S.; J Inherit Metab Dis. 2012 Nov;35(6):1001-9. doi: 10.1007/s10545-012-9473-2. Epub 2012 Mar 24.

22363697 - Role of Chd7 in zebrafish: a model for CHARGE syndrome.
Patten SA, Jacobs-McDaniels NL, Zaouter C, Drapeau P, Albertson RC, Moldovan F.; PLoS One. 2012;7(2):e31650. doi: 10.1371/journal.pone.0031650. Epub 2012 Feb 20.

22330650 - A rat model of diabetic wound infection for the evaluation of topical antimicrobial therapies.
Mendes JJ, Leandro CI, Bonaparte DP, Pinto AL.; Comp Med. 2012 Feb;62(1):37-48.

22316420 - Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease.
Ravenstijn PG, Drenth HJ, O'Neill MJ, Danhof M, de Lange EC.; Fluids Barriers CNS. 2012 Feb 8;9:4. doi: 10.1186/2045-8118-9-4.

22244974 - Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats.
Ehrlich D, Pirchl M, Humpel C.; Neuroscience. 2012 Mar 15;205:154-66. doi: 10.1016/j.neuroscience.2011.12.054. Epub 2012 Jan 5.

22214848 - Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia.
Lee HY, Nakayama J, Xu Y, Fan X, Karouani M, Shen Y, Pothos EN, Hess EJ, Fu YH, Edwards RH, Pt cek LJ.; J Clin Invest. 2012 Feb 1;122(2):507-18. doi: 10.1172/JCI58470. Epub 2012 Jan 3.

22032926 - Glucocorticoid receptors in the prefrontal cortex regulate stress-evoked dopamine efflux and aspects of executive function.
Butts KA, Weinberg J, Young AH, Phillips AG.; Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18459-64. doi: 10.1073/pnas.1111746108. Epub 2011 Oct 27.

22015977 - Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
Duszczyk-Budhathoki M, Olczak M, Lehner M, Majewska MD.; Neurochem Res. 2012 Feb;37(2):436-47. doi: 10.1007/s11064-011-0630-z. Epub 2011 Oct 21.

21957162 - Rate of fall in blood glucose and recurrent hypoglycemia affect glucose dynamics and noradrenergic activation in the ventromedial hypothalamus.
Barnes MB, Lawson MA, Beverly JL.; Am J Physiol Regul Integr Comp Physiol. 2011 Dec;301(6):R1815-20. doi: 10.1152/ajpregu.00171.2011. Epub 2011 Sep 28.

21951066 - The oxysterol 27-hydroxycholesterol regulates ×?-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease.
Marwarha G, Rhen T, Schommer T, Ghribi O.; J Neurochem. 2011 Dec;119(5):1119-36. doi: 10.1111/j.1471-4159.2011.07497.x. Epub 2011 Oct 24.

21871902 - L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease.
King JM, Muthian G, Mackey V, Smith M, Charlton C.; Life Sci. 2011 Oct 24;89(17-18):638-43. doi: 10.1016/j.lfs.2011.08.008. Epub 2011 Aug 18.

21745564 - Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity.
Sledge D, Yen J, Morton T, Dishaw L, Petro A, Donerly S, Linney E, Levin ED.; Neurotoxicol Teratol. 2011 Nov-Dec;33(6):742-51. doi: 10.1016/j.ntt.2011.06.005. Epub 2011 Jul 2.

21741476 - Persistent behavioral impairment caused by embryonic methylphenidate exposure in zebrafish.
Levin ED, Sledge D, Roach S, Petro A, Donerly S, Linney E.; Neurotoxicol Teratol. 2011 Nov-Dec;33(6):668-73. doi: 10.1016/j.ntt.2011.06.004. Epub 2011 Jul 7.

21734276 - Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats.
Miczek KA, Nikulina EM, Shimamoto A, Covington HE 3rd.; J Neurosci. 2011 Jul 6;31(27):9848-57. doi: 10.1523/JNEUROSCI.0637-11.2011.

21722577 - Modulation of the foreign body reaction for implants in the subcutaneous space: microdialysis probes as localized drug delivery/sampling devices.
Mou X, Lennartz MR, Loegering DJ, Stenken JA.; J Diabetes Sci Technol. 2011 May 1;5(3):619-31.

21615684 - Altered ADAR 2 equilibrium and 5HT(2C) R editing in the prefrontal cortex of ADAR 2 transgenic mice.
Singh M, Singh MM, Na E, Agassandian K, Zimmerman MB, Johnson AK.; Genes Brain Behav. 2011 Aug;10(6):637-47. doi: 10.1111/j.1601-183X.2011.00701.x. Epub 2011 Jun 13.

21609470 - Biogenic amines and their metabolites are differentially affected in the Mecp2-deficient mouse brain.
Panayotis N, Ghata A, Villard L, Roux JC.; BMC Neurosci. 2011 May 24;12:47. doi: 10.1186/1471-2202-12-47.

21593311 - Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.
Anwar S, Peters O, Millership S, Ninkina N, Doig N, Connor-Robson N, Threlfell S, Kooner G, Deacon RM, Bannerman DM, Bolam JP, Chandra SS, Cragg SJ, Wade-Martins R, Buchman VL.; J Neurosci. 2011 May 18;31(20):7264-74. doi: 10.1523/JNEUROSCI.6194-10.2011.

21576917 - Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice.
Shelkovnikova TA, Ustyugov AA, Millership S, Peters O, Anichtchik O, Spillantini MG, Buchman VL, Bachurin SO, Ninkina NN.; Neurodegener Dis. 2011;8(6):430-7. doi: 10.1159/000324989. Epub 2011 May 12.

21571006 - Accelerated maternal responding following intra-VTA pertussis toxin treatment.
Byrnes JJ, Gleason ED, Schoen MT, Lovelock DF, Carini LM, Byrnes EM, Bridges RS.; Behav Brain Res. 2011 Oct 1;223(2):322-8. doi: 10.1016/j.bbr.2011.04.048. Epub 2011 May 6.

21569243 - A metabolic biofuel cell: conversion of human leukocyte metabolic activity to electrical currents.
Justin GA, Zhang Y, Cui XT, Bradberry CW, Sun M, Sclabassi RJ.; J Biol Eng. 2011 May 10;5:5. doi: 10.1186/1754-1611-5-5.

21557885 - Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; Int J Neuropsychopharmacol. 2012 May;15(4):485-96. doi: 10.1017/S1461145711000599. Epub 2011 Apr 18.

21480692 - The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects.
Nelson AJ, Cooper MT, Thur KE, Marsden CA, Cassaday HJ.; Behav Neurosci. 2011 Jun;125(3):396-403. doi: 10.1037/a0023337.

21408191 - Progressive neurodegeneration or endogenous compensation in an animal model of Parkinson's disease produced by decreasing doses of alpha-synuclein.
Koprich JB, Johnston TH, Huot P, Reyes MG, Espinosa M, Brotchie JM.; PLoS One. 2011 Mar 7;6(3):e17698. doi: 10.1371/journal.pone.0017698.

21383081 - Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model.
Choi WS, Palmiter RD, Xia Z.; J Cell Biol. 2011 Mar 7;192(5):873-82. doi: 10.1083/jcb.201009132.

21262855 - Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; J Psychopharmacol. 2011 Dec;25(12):1649-60. doi: 10.1177/0269881110389211. Epub 2011 Jan 24.

21209205 - Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioning.
Ostlund SB, Wassum KM, Murphy NP, Balleine BW, Maidment NT.; J Neurosci. 2011 Jan 5;31(1):200-7. doi: 10.1523/JNEUROSCI.4759-10.2011.

21171669 - Safety, tolerability, and pharmacokinetics of etamicastat, a novel dopamine-×?-hydroxylase inhibitor, in a rising multiple-dose study in young healthy subjects.
Nunes T, Rocha JF, Vaz-da-Silva M, Igreja B, Wright LC, Falc?o A, Almeida L, Soares-da-Silva P.; Drugs R D. 2010;10(4):225-42. doi: 10.2165/11586310-000000000-00000.

21152205 - Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression-An Animal Model Study.
Malkesman O, Asaf T, Shbiro L, Goldstein A, Maayan R, Weizman A, Kinor N, Okun E, Sredni B, Yadid G, Weller A.; Adv Pharmacol Sci. 2009;2009:405107. doi: 10.1155/2009/405107. Epub 2009 Oct 18.

21133535 - Dissociable roles of dopamine within the core and medial shell of the nucleus accumbens in memory for objects and place.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; Behav Neurosci. 2010 Dec;124(6):789-99. doi: 10.1037/a0021114.

21042794 - Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice.
Cassano T, Gaetani S, Macheda T, Laconca L, Romano A, Morgese MG, Cimmino CS, Chiarotti F, Bambico FR, Gobbi G, Cuomo V, Piomelli D.; Psychopharmacology (Berl). 2011 Mar;214(2):465-76. doi: 10.1007/s00213-010-2051-0. Epub 2010 Nov 2.

20981353 - Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice.
Hurko O, Boudonck K, Gonzales C, Hughes ZA, Jacobsen JS, Reinhart PH, Crowther D.; Int J Alzheimers Dis. 2010 Oct 11;2010:864625. doi: 10.4061/2010/864625.

20934452 - The potential and limitations of DOV 216,303 as a triple reuptake inhibitor for the treatment of major depression: a microdialysis study in olfactory bulbectomized rats.
Prins J, Westphal KG, Korte-Bouws GA, Quinton MS, Schreiber R, Olivier B, Korte SM.; Pharmacol Biochem Behav. 2011 Jan;97(3):444-52. doi: 10.1016/j.pbb.2010.10.001. Epub 2010 Oct 8.

20934393 - Biogenic amines and their metabolites in mouse brain tissue: development, optimization and validation of an analytical HPLC method.
Nguyen AT, Aerts T, Van Dam D, De Deyn PP.; J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Nov 1;878(29):3003-14. doi: 10.1016/j.jchromb.2010.09.019. Epub 2010 Sep 29.

20864506 - The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties.
Caldarone BJ, Paterson NE, Zhou J, Brunner D, Kozikowski AP, Westphal KG, Korte-Bouws GA, Prins J, Korte SM, Olivier B, Ghavami A.; J Pharmacol Exp Ther. 2010 Dec;335(3):762-70. doi: 10.1124/jpet.110.174011. Epub 2010 Sep 23.

20844316 - Adult-onset, short-term dietary restriction reduces cell senescence in mice.
Wang C, Maddick M, Miwa S, Jurk D, Czapiewski R, Saretzki G, Langie SA, Godschalk RW, Cameron K, von Zglinicki T.; Aging (Albany NY). 2010 Sep;2(9):555-66.

20739551 - Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis.
Robertson SD, Matthies HJ, Owens WA, Sathananthan V, Christianson NS, Kennedy JP, Lindsley CW, Daws LC, Galli A.; J Neurosci. 2010 Aug 25;30(34):11305-16. doi: 10.1523/JNEUROSCI.0126-10.2010.

20649591 - Preferential in vivo action of F15599, a novel 5-HT(1A) receptor agonist, at postsynaptic 5-HT(1A) receptors.
Llad?-Pelfort L, Assi‚ MB, Newman-Tancredi A, Artigas F, Celada P.; Br J Pharmacol. 2010 Aug;160(8):1929-40. doi: 10.1111/j.1476-5381.2010.00738.x.

20649576 - Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease.
Austin PJ, Betts MJ, Broadstock M, O'Neill MJ, Mitchell SN, Duty S.; Br J Pharmacol. 2010 Aug;160(7):1741-53. doi: 10.1111/j.1476-5381.2010.00820.x.

20619321 - Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition.
Nelson AJ, Thur KE, Marsden CA, Cassaday HJ.; Neuroscience. 2010 Sep 29;170(1):99-106. doi: 10.1016/j.neuroscience.2010.06.066. Epub 2010 Jul 7.

20615977 - Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA-induced dyskinesia in rats.
Ulusoy A, Sahin G, Kirik D.; Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13159-64. doi: 10.1073/pnas.1003432107. Epub 2010 Jul 6.

20590604 - WAY-318068: a novel, potent and selective noradrenaline re-uptake inhibitor with activity in rodent models of pain and depression.
Whiteside GT, Dwyer JM, Harrison JE, Beyer CE, Cummons T, Manzino L, Mark L, Johnston GH, Strassle BW, Adedoyin A, Lu P, Piesla MJ, Pulicicchio CM, Erve JC, Platt BJ, Hughes ZA, Rogers KE, Deecher DC, Trybulski EJ, Kennedy JD, Zhang P, Leventhal L.; Br J Pharmacol. 2010 Jul;160(5):1105-18. doi: 10.1111/j.1476-5381.2010.00690.x.

20579004 - Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system.
Jerlhag E, Egecioglu E, Dickson SL, Engel JA.; Addict Biol. 2011 Jan;16(1):82-91. doi: 10.1111/j.1369-1600.2010.00231.x.

20559820 - Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference.
Jerlhag E, Egecioglu E, Dickson SL, Engel JA.; Psychopharmacology (Berl). 2010 Sep;211(4):415-22. doi: 10.1007/s00213-010-1907-7. Epub 2010 Jun 19.

20540993 - Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration.
Muthian G, Mackey V, King J, Charlton CG.; Neuroscience. 2010 Sep 1;169(3):1085-93. doi: 10.1016/j.neuroscience.2010.04.080. Epub 2010 Jun 9.

20477752 - Ghrelin increases intake of rewarding food in rodents.
Egecioglu E, Jerlhag E, Salom‚ N, Skibicka KP, Haage D, Bohlooly-Y M, Andersson D, Bjursell M, Perrissoud D, Engel JA, Dickson SL.; Addict Biol. 2010 Jul;15(3):304-11. doi: 10.1111/j.1369-1600.2010.00216.x. Epub 2010 May 6.

20364890 - Is sexual motivational state linked to dopamine release in the medial preoptic area?
Kleitz-Nelson HK, Dominguez JM, Cornil CA, Ball GF.; Behav Neurosci. 2010 Apr;124(2):300-4. doi: 10.1037/a0018767.

20223515 - Long-term calibration considerations during subcutaneous microdialysis sampling in mobile rats.
Mou X, Lennartz MR, Loegering DJ, Stenken JA.; Biomaterials. 2010 Jun;31(16):4530-9. doi: 10.1016/j.biomaterials.2010.02.016. Epub 2010 Mar 11.

20202080 - Nicotine self-administration differentially modulates glutamate and GABA transmission in hypothalamic paraventricular nucleus to enhance the hypothalamic-pituitary-adrenal response to stress.
Yu G, Chen H, Wu X, Matta SG, Sharp BM.; J Neurochem. 2010 May;113(4):919-29. doi: 10.1111/j.1471-4159.2010.06654.x. Epub 2010 Feb 25.

20003525 - Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains.
van der Staay FJ, Schuurman T, van Reenen CG, Korte SM.; Behav Brain Funct. 2009 Dec 15;5:50. doi: 10.1186/1744-9081-5-50.

19948168 - The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: clinical relevance.
Sonsalla PK, Wong LY, Winnik B, Buckley B.; Exp Neurol. 2010 Feb;221(2):329-34. doi: 10.1016/j.expneurol.2009.11.018. Epub 2009 Dec 4.

19906957 - Hyperdopaminergic tone erodes prefrontal long-term potential via a D2 receptor-operated protein phosphatase gate.
Xu TX, Sotnikova TD, Liang C, Zhang J, Jung JU, Spealman RD, Gainetdinov RR, Yao WD.; J Neurosci. 2009 Nov 11;29(45):14086-99. doi: 10.1523/JNEUROSCI.0974-09.2009.

19694908 - Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice.
Kitada T, Tong Y, Gautier CA, Shen J.; J Neurochem. 2009 Nov;111(3):696-702. doi: 10.1111/j.1471-4159.2009.06350.x. Epub 2009 Aug 19.

19654866 - Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex.
Kroener S, Chandler LJ, Phillips PE, Seamans JK.; PLoS One. 2009 Aug 5;4(8):e6507. doi: 10.1371/journal.pone.0006507.

19452129 - A new minimal-stress freely-moving rat model for preclinical studies on intranasal administration of CNS drugs.
Stevens J, Suidgeest E, van der Graaf PH, Danhof M, de Lange EC.; Pharm Res. 2009 Aug;26(8):1911-7. doi: 10.1007/s11095-009-9907-1. Epub 2009 May 19.

19413648 - The dopamine response in the nucleus accumbens core-shell border differs from that in the core and shell during operant ethanol self-administration.
Howard EC, Schier CJ, Wetzel JS, Gonzales RA.; Alcohol Clin Exp Res. 2009 Aug;33(8):1355-65. doi: 10.1111/j.1530-0277.2009.00965.x. Epub 2009 Apr 30.

19409204 - Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity.
Geiger BM, Haburcak M, Avena NM, Moyer MC, Hoebel BG, Pothos EN.; Neuroscience. 2009 Apr 10;159(4):1193-9. doi: 10.1016/j.neuroscience.2009.02.007. Epub 2009 Feb 11.

19389195 - Disparity between tonic and phasic ethanol-induced dopamine increases in the nucleus accumbens of rats.
Robinson DL, Howard EC, McConnell S, Gonzales RA, Wightman RM.; Alcohol Clin Exp Res. 2009 Jul;33(7):1187-96. doi: 10.1111/j.1530-0277.2009.00942.x. Epub 2009 Apr 9.

19338583 - Preclinical characterization of WAY-211612: a dual 5-HT uptake inhibitor and 5-HT (1A) receptor antagonist and potential novel antidepressant.
Beyer CE, Lin Q, Platt B, Malberg J, Hornby G, Sullivan KM, Smith DL, Lock T, Mitchell PJ, Hatzenbuhler NT, Evrard DA, Harrison BL, Magolda R, Pangalos MN, Schechter LE, Rosenzweig-Lipson S, Andree TH.; Br J Pharmacol. 2009 May;157(2):307-19. doi: 10.1111/j.1476-5381.2009.00146.x. Epub 2009 Mar 26.

19322939 - Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.
Gallos G, Gleason NR, Virag L, Zhang Y, Mizuta K, Whittington RA, Emala CW.; Anesthesiology. 2009 Apr;110(4):748-58.

19295143 - Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy.
Chung CY, Koprich JB, Siddiqi H, Isacson O.; J Neurosci. 2009 Mar 18;29(11):3365-73. doi: 10.1523/JNEUROSCI.5427-08.2009.

19278906 - Analysis of BNP7787 thiol-disulfide exchange reactions in phosphate buffer and human plasma using microscale electrochemical high performance liquid chromatography.
Shanmugarajah D, Ding D, Huang Q, Chen X, Kochat H, Petluru PN, Ayala PY, Parker AR, Hausheer FH.; J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Apr 1;877(10):857-66. doi: 10.1016/j.jchromb.2009.02.056. Epub 2009 Feb 28.

19268529 - Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits.
Eddins D, Cerutti D, Williams P, Linney E, Levin ED.; Neurotoxicol Teratol. 2010 Jan-Feb;32(1):99-108. doi: 10.1016/j.ntt.2009.02.005. Epub 2009 Mar 4.

19228951 - Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW.; J Neurosci. 2009 Feb 18;29(7):1962-76. doi: 10.1523/JNEUROSCI.5351-08.2009.

19181487 - Dopamine and serotonin release in the nucleus accumbens during starvation-induced hyperactivity.
Verhagen LA, Luijendijk MC, Korte-Bouws GA, Korte SM, Adan RA.; Eur Neuropsychopharmacol. 2009 May;19(5):309-16. doi: 10.1016/j.euroneuro.2008.12.008. Epub 2009 Jan 31.

19014385 - Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells.
Rantham Prabhakara JP, Feist G, Thomasson S, Thompson A, Schommer E, Ghribi O.; J Neurochem. 2008 Dec;107(6):1722-9. doi: 10.1111/j.1471-4159.2008.05736.x. Epub 2008 Nov 5.

19010365 - Neurochemical changes in the striatum of dyskinetic rats after administration of the cannabinoid agonist WIN55,212-2.
Morgese MG, Cassano T, Gaetani S, Macheda T, Laconca L, Dipasquale P, Ferraro L, Antonelli T, Cuomo V, Giuffrida A.; Neurochem Int. 2009 Jan;54(1):56-64. doi: 10.1016/j.neuint.2008.10.007. Epub 2008 Nov 1.

18977370 - Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens.
Leggio GM, Cathala A, Moison D, Cunningham KA, Piazza PV, Spampinato U.; Neuropharmacology. 2009 Feb;56(2):507-13. doi: 10.1016/j.neuropharm.2008.10.005. Epub 2008 Oct 17.

18959477 - An autonomous circadian clock in the inner mouse retina regulated by dopamine and GABA.
Ruan GX, Allen GC, Yamazaki S, McMahon DG.; PLoS Biol. 2008 Oct 14;6(10):e249. doi: 10.1371/journal.pbio.0060249.

18818210 - Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.
Chou AP, Maidment N, Klintenberg R, Casida JE, Li S, Fitzmaurice AG, Fernagut PO, Mortazavi F, Chesselet MF, Bronstein JM.; J Biol Chem. 2008 Dec 12;283(50):34696-703. doi: 10.1074/jbc.M802210200. Epub 2008 Sep 25.

18704096 - Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease.
De Leonibus E, Manag? F, Giordani F, Petrosino F, Lopez S, Oliverio A, Amalric M, Mele A.; Neuropsychopharmacology. 2009 Feb;34(3):729-38. doi: 10.1038/npp.2008.129. Epub 2008 Aug 13.

18653657 - Afferent hypersensitivity in a mouse model of post-inflammatory gut dysfunction: role of altered serotonin metabolism.
Keating C, Beyak M, Foley S, Singh G, Marsden C, Spiller R, Grundy D.; J Physiol. 2008 Sep 15;586(Pt 18):4517-30. doi: 10.1113/jphysiol.2008.156984. Epub 2008 Jul 24.

18579734 - Functional remodeling of gap junction-mediated electrical communication between adrenal chromaffin cells in stressed rats.
Colomer C, Olivos Ore LA, Coutry N, Mathieu MN, Arthaud S, Fontanaud P, Iankova I, Macari F, Thou‰nnon E, Yon L, Anouar Y, Gu‚rineau NC.; J Neurosci. 2008 Jun 25;28(26):6616-26. doi: 10.1523/JNEUROSCI.5597-07.2008.

18511209 - The shell of the nucleus accumbens has a higher dopamine response compared with the core after non-contingent intravenous ethanol administration.
Howard EC, Schier CJ, Wetzel JS, Duvauchelle CL, Gonzales RA.; Neuroscience. 2008 Jun 26;154(3):1042-53. doi: 10.1016/j.neuroscience.2008.04.014. Epub 2008 Apr 16. Erratum in: Neuroscience. 2013 Feb 12;231:444.

18511204 - Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration.
Rezvani AH, Eddins D, Slade S, Hampton DS, Christopher NC, Petro A, Horton K, Johnson M, Levin ED.; Neuroscience. 2008 Jun 26;154(3):885-97. doi: 10.1016/j.neuroscience.2008.04.020. Epub 2008 Apr 16.

18439826 - Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood.
Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, Perreau-Lenz S, Brunk I, Spanagel R, Ahnert-Hilger G, Meijer JH, Albrecht U.; Curr Biol. 2008 May 6;18(9):678-83. doi: 10.1016/j.cub.2008.04.012. Epub 2008 Apr 24.

18353913 - State-dependent changes in glutamate, glycine, GABA, and dopamine levels in cat lumbar spinal cord.
Taepavarapruk N, Taepavarapruk P, John J, Lai YY, Siegel JM, Phillips AG, McErlane SA, Soja PJ.; J Neurophysiol. 2008 Aug;100(2):598-608. doi: 10.1152/jn.01231.2007. Epub 2008 Mar 19.

18226494 - Mercury-induced cognitive impairment in metallothionein-1/2 null mice.
Eddins D, Petro A, Pollard N, Freedman JH, Levin ED.; Neurotoxicol Teratol. 2008 Mar-Apr;30(2):88-95. doi: 10.1016/j.ntt.2007.12.005. Epub 2007 Dec 15.

18178178 - Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice.
Camarini R, Griffin WC 3rd, Yanke AB, Rosalina dos Santos B, Olive MF.; Brain Res. 2008 Feb 8;1193:34-42. doi: 10.1016/j.brainres.2007.11.045. Epub 2007 Dec 5.

17909761 - A low perfusion rate microreactor for continuous monitoring of enzyme characteristics: application to glucose oxidase.
Posthuma-Trumpie GA, Venema K, van Berkel WJ, Korf J.; Anal Bioanal Chem. 2007 Nov;389(6):2029-33. Epub 2007 Oct 2.

17874235 - Medial prefrontal serotonin in the rat is involved in goal-directed behaviour when affect guides decision making.
van der Plasse G, La Fors SS, Meerkerk DT, Joosten RN, Uylings HB, Feenstra MG.; Psychopharmacology (Berl). 2007 Dec;195(3):435-49. Epub 2007 Sep 15.

17822436 - High-frequency stimulation of the subthalamic nucleus prolongs the increase in striatal dopamine induced by acute l-3,4-dihydroxyphenylalanine in dopaminergic denervated rats.
Lacombe E, Carcenac C, Boulet S, Feuerstein C, Bertrand A, Poupard A, Savasta M.; Eur J Neurosci. 2007 Sep;26(6):1670-80. Epub 2007 Sep 6.

17713760 - Lack of evidence for reduced prefrontal cortical serotonin and dopamine efflux after acute tryptophan depletion.
van der Plasse G, Meerkerk DT, Lieben CK, Blokland A, Feenstra MG.; Psychopharmacology (Berl). 2007 Dec;195(3):377-85. Epub 2007 Aug 23.

17693036 - Exposure to novelty and forced swimming evoke stressor-dependent changes in extracellular GABA in the rat hippocampus.
de Groote L, Linthorst AC.; Neuroscience. 2007 Sep 7;148(3):794-805. Epub 2007 Aug 10.

17535435 - Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice.
Yamaguchi H, Shen J.; Mol Neurodegener. 2007 May 29;2:10.

17471182 - Population pharmacokinetic modelling of non-linear brain distribution of morphine: influence of active saturable influx and P-glycoprotein mediated efflux.
Groenendaal D, Freijer J, de Mik D, Bouw MR, Danhof M, de Lange EC.; Br J Pharmacol. 2007 Jul;151(5):701-12. Epub 2007 Apr 30.

17467707 - The effects of nitric oxide-cGMP pathway stimulation on dopamine in the medial preoptic area and copulation in DHT-treated castrated male rats.
Sato SM, Wersinger SR, Hull EM.; Horm Behav. 2007 Aug;52(2):177-82. Epub 2007 Mar 27.

17460150 - Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors.
Zhu CB, Steiner JA, Munn JL, Daws LC, Hewlett WA, Blakely RD.; J Pharmacol Exp Ther. 2007 Jul;322(1):332-40. Epub 2007 Apr 25.

17420778 - Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint.
van Steeg TJ, Freijer J, Danhof M, de Lange EC.; Br J Pharmacol. 2007 Jun;151(3):356-66. Epub 2007 Apr 10.

17324270 - Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.
Pugh PL, Vidgeon-Hart MP, Ashmeade T, Culbert AA, Seymour Z, Perren MJ, Joyce F, Bate ST, Babin A, Virley DJ, Richardson JC, Upton N, Sunter D.; J Neuroinflammation. 2007 Feb 26;4:8.

17293887 - Comparisons between bupropion and dexamphetamine in a range of in vivo tests exploring dopaminergic transmission.
Bredeloux P, Dubuc I, Costentin J.; Br J Pharmacol. 2007 Mar;150(6):711-9. Epub 2007 Feb 12.

17259364 - Piezotolerant small-colony variants with increased thermotolerance, antibiotic susceptibility, and low invasiveness in a clonal Staphylococcus aureus population.
Karatzas KA, Zervos A, Tassou CC, Mallidis CG, Humphrey TJ.; Appl Environ Microbiol. 2007 Mar;73(6):1873-81. Epub 2007 Jan 26.

17105171 - Microdialysis sampling extraction efficiency of 2-deoxyglucose: role of macrophages in vitro and in vivo.
Mou X, Stenken JA.; Anal Chem. 2006 Nov 15;78(22):7778-84.

16800896 - Effects of autologous bone marrow stem cell transplantation on beta-adrenoceptor density and electrical activation pattern in a rabbit model of non-ischemic heart failure.
Dhein S, Garbade J, Rouabah D, Abraham G, Ungemach FR, Schneider K, Ullmann C, Aupperle H, Gummert JF, Mohr FW.; J Cardiothorac Surg. 2006 Jun 26;1:17.

16781738 - Kappa-opioid receptor modulation of accumbal dopamine concentration during operant ethanol self-administration.
Doyon WM, Howard EC, Shippenberg TS, Gonzales RA.; Neuropharmacology. 2006 Sep;51(3):487-96. Epub 2006 Jun 15.

16764833 - Pharmacokinetic and pharmacodynamic profiles of the novel serotonin and norepinephrine reuptake inhibitor desvenlafaxine succinate in ovariectomized Sprague-Dawley rats.
Alfinito PD, Huselton C, Chen X, Deecher DC.; Brain Res. 2006 Jul 7;1098(1):71-8. Epub 2006 Jun 9.

16641229 - Neuroprotection by transgenic expression of glucose-6-phosphate dehydrogenase in dopaminergic nigrostriatal neurons of mice.
Mejˇas R, Villadiego J, Pintado CO, Vime PJ, Gao L, Toledo-Aral JJ, Echevarrˇa M, L?pez-Barneo J.; J Neurosci. 2006 Apr 26;26(17):4500-8.

15999145 - Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex.
Pehek EA, Nocjar C, Roth BL, Byrd TA, Mabrouk OS.; Neuropsychopharmacology. 2006 Feb;31(2):265-77.

15999145 - Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex.
Pehek EA, Nocjar C, Roth BL, Byrd TA, Mabrouk OS.; Neuropsychopharmacology. 2006 Feb;31(2):265-77.

15678098 - Postsynaptic 5-HT1B receptors modulate electroshock-induced generalised seizures in rats.
Stean TO, Atkins AR, Heidbreder CA, Quinn LP, Trail BK, Upton N.; Br J Pharmacol. 2005 Mar;144(5):628-35.

15655523 - Anxiogenic properties of an inverse agonist selective for alpha3 subunit-containing GABA A receptors.
Atack JR, Hutson PH, Collinson N, Marshall G, Bentley G, Moyes C, Cook SM, Collins I, Wafford K, McKernan RM, Dawson GR.; Br J Pharmacol. 2005 Feb;144(3):357-66.

15083199 - Pharmacokinetic behaviour of the chemoprotectants BNP7787 and mesna after an i.v. bolus injection in rats.
Verschraagen M, Boven E, Torun E, Erkelens CA, Hausheer FH, van der Vijgh WJ.; Br J Cancer. 2004 Apr 19;90(8):1654-9.

11564647 - Effects of imidazoline antihypertensive drugs on sympathetic tone and noradrenaline release in the prefrontal cortex.
Szabo B, Fritz T, Wedzony K.; Br J Pharmacol. 2001 Sep;134(2):295-304.

11564645 - A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats.
Serra PA, Rocchitta G, Esposito G, Delogu MR, Migheli R, Miele E, Desole MS, Miele M.; Br J Pharmacol. 2001 Sep;134(2):275-82.

11390648 - Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice.
Zwart R, Verhaagh S, Buitelaar M, Popp-Snijders C, Barlow DP.; Mol Cell Biol. 2001 Jul;21(13):4188-96.

11181436 - Analysis of S-nitroso-N-acetylpenicillamine effects on dopamine release in the striatum of freely moving rats: role of endogenous ascorbic acid and oxidative stress.
Serra PA, Esposito G, Delogu MR, Migheli R, Rocchitta G, Miele E, Desole MS, Miele M.; Br J Pharmacol. 2001 Feb;132(4):941-9.

11139433 - Circadian variation in the activity of the 5-HT(1B) autoreceptor in the region of the suprachiasmatic nucleus, measured by microdialysis in the conscious freely-moving rat.
Garabette ML, Martin KF, Redfern PH.; Br J Pharmacol. 2000 Dec;131(8):1569-76.

11030735 - Analysis of 3-morpholinosydnonimine and sodium nitroprusside effects on dopamine release in the striatum of freely moving rats: role of nitric oxide, iron and ascorbic acid.
Serra PA, Esposito G, Delogu MR, Migheli R, Rocchitta G, Grella G, Miele E, Miele M, Desole MS.; Br J Pharmacol. 2000 Oct;131(4):836-42.

10864903 - Manganese increases L-DOPA auto-oxidation in the striatum of the freely moving rat: potential implications to L-DOPA long-term therapy of Parkinson's disease.
Serra PA, Esposito G, Enrico P, Mura MA, Migheli R, Delogu MR, Miele M, Desole MS, Grella G, Miele E.; Br J Pharmacol. 2000 Jun;130(4):937-45.

10864885 - Effects of chronic fluoxetine treatment in the presence and absence of (+/-)pindolol: a microdialysis study.
Dawson LA, Nguyen HQ, Smith DI, Schechter LE.; Br J Pharmacol. 2000 Jun;130(4):797-804.

10780993 - In vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate.
Dawson LA, Nguyen HQ, Li P.; Br J Pharmacol. 2000 May;130(1):23-6.

10742291 - The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.
Treseder SA, Jackson M, Jenner P.; Br J Pharmacol. 2000 Apr;129(7):1355-64.

10711358 - On the mechanism of d-amphetamine-induced changes in glutamate, ascorbic acid and uric acid release in the striatum of freely moving rats.
Miele M, Mura MA, Enrico P, Esposito G, Serra PA, Migheli R, Zangani D, Miele E, Desole MS.; Br J Pharmacol. 2000 Feb;129(3):582-8.

10675353 - Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.
Wijnholds J, deLange EC, Scheffer GL, van den Berg DJ, Mol CA, van der Valk M, Schinkel AH, Scheper RJ, Breimer DD, Borst P.; J Clin Invest. 2000 Feb;105(3):279-85.

10417495 - The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers.
Van Haarst AD, Van Gerven JM, Cohen AF, De Smet M, Sterrett A, Birk KL, Fisher AL, De Puy ME, Goldberg MR, Musson DG.; Br J Clin Pharmacol. 1999 Aug;48(2):190-6.

9797725 - The identification of salicylates as normal constituents of serum: a link between diet and health?
Paterson JR, Blacklock C, Campbell G, Wiles D, Lawrence JR.; J Clin Pathol. 1998 Jul;51(7):502-5.

9171994 - Possible relevance of pigeons as an indicator species for monitoring air pollution.
Schilderman PA, Hoogewerff JA, van Schooten FJ, Maas LM, Moonen EJ, van Os BJ, van Wijnen JH, Kleinjans JC.; Environ Health Perspect. 1997 Mar;105(3):322-30.

8825343 - Ability of 5-HT4 receptor ligands to modulate rat striatal dopamine release in vitro and in vivo.
Steward LJ, Ge J, Stowe RL, Brown DC, Bruton RK, Stokes PR, Barnes NM.; Br J Pharmacol. 1996 Jan;117(1):55-62.

8735646 - Ability of angiotensin II to modulate striatal dopamine release via the AT1 receptor in vitro and in vivo.
Brown DC, Steward LJ, Ge J, Barnes NM.; Br J Pharmacol. 1996 May;118(2):414-20.

8730742 - 5-HT4 receptor-mediated modulation of 5-HT release in the rat hippocampus in vivo.
Ge J, Barnes NM.; Br J Pharmacol. 1996 Apr;117(7):1475-80.

8719805 - Differential effects of potassium channel blockers on extracellular concentrations of dopamine and 5-HT in the striatum of conscious rats.
Dawson LA, Routledge C.; Br J Pharmacol. 1995 Dec;116(8):3260-4.

8581296 - Application of intracerebral microdialysis to study regional distribution kinetics of drugs in rat brain.
de Lange EC, Bouw MR, Mandema JW, Danhof M, de Boer AG, Breimer DD.; Br J Pharmacol. 1995 Nov;116(5):2538-44.

8564217 - 5-HT3 receptor agonist induced carrier-mediated release of dopamine in rat striatum in vivo.
Santiago M, Machado A, Cano J.; Br J Pharmacol. 1995 Sep;116(1):1545-50.

8319636 - Determining N7-alkylguanine adducts by immunochemical methods and HPLC with electrochemical detection: applications in animal studies and in monitoring human exposure to alkylating agents.
van Delft JH, van Winden MJ, van den Ende AM, Baan RA.; Environ Health Perspect. 1993 Mar;99:25-32.

8019760 - Effect of L-arginine/nitric oxide pathway on MPP(+)-induced cell injury in the striatum of rats.
Santiago M, Machado A, Cano J.; Br J Pharmacol. 1994 Mar;111(3):837-42.

7689406 - In vivo release of dopamine from rat striatum, substantia nigra and prefrontal cortex: differential modulation by baclofen.
Santiago M, Machado A, Cano J.; Br J Pharmacol. 1993 Jul;109(3):814-8.

26116760 - Central serotonin2B receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow
Devroye C1, Cathala A2, Di Marco B3, Caraci F4, Drago F5, Piazza PV6, Spampinato U7.; Neuropharmacology.˙2015 Oct;97:329-37. doi: 10.1016/j.neuropharm.2015.06.012. Epub 2015 Jun 25.