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Applications » Neurotransmitters » GABA and Glutamate

GABA and Glutamate

HPLC analysis of GABA and Glutamate

  • Fully automated ‘in-needle’ OPA derivatization
  • Post separation ‘wash’ to eliminate late eluters
  • Small sample use of 5 µL
  • Suitable for histamine and other LNAA’s

The ALEXYS Neurotransmitter Analyzer is a modular system that can be customized for the analysis of specific neurotransmitters. A sensitive method has been developed for the analysis of the amino acid neurotransmitters GABA and glutamate, as well as histamine and several other LNAA’s (large neutral amino acids). It has a fully automated OPA derivatisation procedure using an AS 110 user program. Late eluting peaks from the OPA reagent are conveniently removed by an automated wash step. GABA/Glu analyzer can be down-scaled to a sample volume < 10 µL.