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Recent publications using ROXY Electrochemistry-MS

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Read the latest publications using the ROXY™ EC system

Over 90% of the world’s existing compounds possess REDOX properties, making them either oxidizable or reducible. By injecting your analyte into an electrochemical cell and identifying the reaction products by MS, many of nature’s REDOX reactions can be mimicked (simulated) within seconds without any biological interactions, making on-line EC-MS the technique of choice.

Drug Metabolism

  • Simulation of sildenafil metabolism using an electrochemical oxidation system, Unyong Kim et al. Read more
  • Study of oxidation products of morphine and their reactivity by electrochemistry/(liquid chromatography/)mass spectrometry, Semyon K. IIyushonok et al. Read more
  • A new one-pot technique for obtaining potential indapamide metabolites by oxidation and conjugation on maldi target, Olga A. Keltsieva et al. Read more
  • Electrochemical simulation of psychotropic drug metabolism compared to in vivo processes using liquid chromatography and mass spectrometry, Paulina Jerszyńska and Małgorzata Szultka-Młyńska. Read more
  • Electrochemistry Coupled to High-Resolution Mass Spectrometry for Phase I and Phase II Metabolic Studies of Bioactive Constituents in Phellodendri Chinensis Cortex, Man Yang et al. Read more
  • Electrochemical Simulation of 25B-NBOMe Phase I Metabolism and Metabolite Profiling by HPLC-QTOF-MS, Agata Kot-Wasik et al. Read more
  • Electrochemistry–Mass Spectrometry for Generation and Identification of Metabolites of Selected Drugs from Different Therapeutic Groups in Comparison with In Vitro and In Vivo Approaches, Małgorzata Szultka-Młyńska. Read more

Drug Stability

  • Oxidation and Reduction of Hydrazones—Risk Factors Related to the Manufacture and Stability of the Drugs, Anna B. Witkowska et al. Read more

Environmental Degradation

  • Monitoring of the electrochemical oxidation of venlafaxine and its metabolite o-desmethylvenlafaxine using a flow cell and high-resolution mass spectrometry, Melanie Voigt et al. Read more

Review

  • Mass spectrometric methods for the analysis of electrochemical transformation products, Valentin Göldner et al. Read more

ROXY Brochure

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