Can I use my detector in strongly alkaline or acid media?

Applies to

Electrochemical detection

Answer

Yes, the electrochemical flow cell is the wetted part in electrochemical detection and it can be used between pH 1 and 14. Metal working electrodes may have a short lifetime in strongly acidic environment. At high pH the background current will be high because of oxidation of the metal. At extreme pH values, a HyREF reference electrode is advised. An ISAAC reference electrode can be used between pH 2 and 9. It is recommended, to switch to a less concentrated buffer when not in use.

Warning: read manufacturers instructions for pH resistance of other parts of your LC-EC system, such as inlet filters, column and pump.