The µ-PrepCell™ is the perfect workhorse to perform electrochemical reactions with high conversion efficiencies at flow rates up to 200 µl/min. Two versions are available. The µ-PrepCell 2.0 is the best choice for oxidative metabolism and degradation studies, while the µ-PrepCell SS is a dedicated cell for efficient disulfide bond reduction in peptides and proteins.
For oxidative reactions the µ-PrepCell 2.0 is the cell of choice providing highest selectivity and high yield by the availability of different working electrodes such as Glassy Carbon (GC), Magic Diamond™ (BDD: Boron Doped Diamond), Au and Pt. The large working potential of 0-4V by using BDD as working electrode is another benefit of the cell-electrode assembly that allows generating .OH radicals the most powerful oxidizing agent. The cell can be disassembled within a few seconds for easy cleaning or exchange of working electrode, making the µ-PrepCell 2.0 the ideal workhorse for oxidative reactions.
For the reduction of disulfide bonds in peptides/proteins including mAbs the newly developed µ-PrepCell SS is the cell of choice. Unlike the chemical reduction using harsh reagents such as DTT or TECP that often interfere with the LC-MS analysis, or costly enzymes, the on-line electrochemical reduction is a real green approach resulting in superior characterization of proteins in top-down and bottom-up proteomics including
|204.4304||μ-PrepCell SS, consisting of:
μ-PrepCell with mounting bracket, cell cable, spacers, Ti working electrode (inlet block) and
Pt counter electrode for disulfide (S-S) bond reduction.
|204.4310||μ-PrepCell 2.0 GC/BDD, consisting of:
μ-PrepCell 2.0 with mounting bracket, cell cable, spacers, Pd/H2 reference electrode (HyREF) and
working electrodes: Glassy Carbon (GC), Magic Diamond (BDD), 1 each.
|204.5007||Glassy Carbon (GC) working electrode|
|204.5050||Magic Diamond (BDD) working electrode|
|204.5022||Platinum (Pt) working/counter electrode
|204.5027||Gold (Au) working electrode
|204.0913||HyREF for µ-PrepCell
|204.0501||O-ring inlet block, Silicone, 5pcs
|204.0506||O-ring inlet block, Silicone, 5pcs
|204.0503||O-ring REF electrode, Silicone, 5pcs
|204.0505||O-ring inlet block, Kalrez, 5pcs
|204.2217||Spacer 50 µm
|204.2218||Spacer 100 µm|
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