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Hydrogen Deuterium Exchange MS is a powerful and flexible method for epitope mapping. As therapeutic targets increase in complexity, sophisticated analytical methods are necessary for detailed and complete insights with HDX-MS. Online electrochemical reduction has emerged as a versatile tool for enhancing sequence coverage in heavily-disulfide bonded antigens.

Visit our poster or meet with Martin Eysberg at the HDX MS 2022 Congress, April 24-26, London, UK, to get an update on our latest developments in electrochemistry for HDXMS.