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Rolduc 2016

Electrochemical reactors for MS

 

 

With almost 200 peer publications over the last 5 years, Electrochemistry used as reaction technology to mimic nature''s REDOX reactions is gaining increasing acceptance in academia as well as industry. The on-line coupling of Electrochemistry (EC) with LC/MS has shown great potential for the fast investigation of drug metabolism (phase I and II), and in research fields such as cleavage of disulfide bonds in proteins/peptides without the need of interfering chemicals (DTT, TCEP), fast and straightforward (enantio-) selective synthesis of metabolites and degradants. The ROXY EC system with its dedicated flow cells provide all the tools for successful EC/MS research. 

Poster presentations