Antec Scientific is a spin-off of the University of Leiden (The Netherlands), where in the mid 80’ two scientists developed a new electrochemical flow cell using a wall-jet concept. This Wall-Jet flow cell showed superior robustness, reproducibility and sensitivity than any other on the market and was the base together with the company Spark Holland to found Antec Scientific. Today, this Wall-Jet flow cell in its 2nd generation is still the most sensitive electrochemical cell and sold under the tradename SenCell™
To obtain the best detection sensitivity it was necessary to develop an electrochemical detector (ECD) with a precisely controlled temperature compartment to accommodate the cell as well as the HPLC column. In the mid 90’ the Antec Scientific introduced its 1st electrochemical detectors. In 2016 the 4th generation of ECD detectors has been introduced to the market know as DECADE™ Elite and Lite.
In 2005, Antec became a provider of guaranteed and dedicated HPLC/ECD applications. With the introduction of the ALEXYS™ Analysers, Antec has optimized all parts of the HPLC system such as pump(s), autosampler and fluidics, to produce the best possible performance and ease of use. Today, dedicated turn-key ALEXYS Analysers are available for a broad range of applications.
Another milestone was achieved in 2009, when Antec Scientific introduced the ROXY™ EC system to the MS community. Herewith, the on-line coupling of EC/MS has become reality. The use of electrochemical reactors up-front MS allows to study and mimic most of nature’s REDOX reactions in real time without any biological interference. More than 100 peer-reviewed publications are proof of this fast growing and exciting technology.
Recently, the use of electrochemical synthesis in bulk solution or in flow chemistry has shown great potential for fast synthesis of drug variants, metabolites, degradants, etc. Our µ-PrepCell™ and SynthesisCell™ are the ideal tools for these applications.